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. 2021 Aug 4;44(11):1209–1214. doi: 10.1007/s40264-021-01104-9

Table 2.

Characteristics of reported anaphylaxis (Brighton level 1, 2 or 3) after COVID-19 vaccination in Japan (14 February–21 March 2021)

Characteristics No. of cases (%) [n = 47]
Age, years [median (range)] 41 (22–56)
Female sex 44 (94)
Time to onset, min [median (range)] 10 (< 1–480)
Symptom onset, min
 ≤ 5 30 (64)
 ≤ 30 41 (87)
 > 30 6 (13)
Prior allergic history
 Allergies and allergic reaction to food, drug, pollen, animals 34 (72)
 Prior anaphylaxis 1 (2)
Vaccine doses
 First 45
 Second 2
Brighton level
 1 7 (15)
 2 33 (70)
 3 7 (15)
Anaphylaxis reporting rate 8.1/100,000

Data are expressed as n (%) unless otherwise specified

COVID-19 coronavirus disease 2019