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. 2021 Aug 3;7(2):e001726. doi: 10.1136/rmdopen-2021-001726

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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(A) Principal component analysis biplot of serum cytokine levels in HCs (n=50) and Modic change (MC) type 1 (n=37) and MC type 2 (n=46) showing the healthy controls' individual scores as orange circles, and patients’ individual scores as blue triangles in the first principal component (PC1) and second principal component (PC2), as well as cytokine loadings as black arrows. (B) The two first PCs are plotted with the proportion of variance explained by each component indicated next to the axis label.