Table 3.
Various biomarkers for CVD before (baseline) and after a 8-week ingestion of control or saury oil supplement
Baseline (n=30) | Control oil (n=30) | Saury oil (n=30) | ||||
---|---|---|---|---|---|---|
Mean | SD/IQR | Mean | SD/IQR | Mean | SD/IQR | |
Clinical and laboratory values | ||||||
hsCRP (mg/L) (0 – 4.99) |
2.4 | 0.5-3.0 | 1.4 | 0.4-2.2 | 1.6 | 0.3-2.3 |
AST (U/L) (0 – 32) |
21.9 | 13.8 | 20.6 | 6.2 | 20.9 | 6.3 |
ALT (U/L) (0 – 33) |
18.2 | 9.9 | 18 | 6.9 | 19.8 | 12.3 |
TSH (μlU/mL) (0.27 – 4.20) |
2.1 | 1.4 | 2.2 | 1.3 | 2.1 | 1.1 |
Uric Acid (mg/dL) (2.4 – 5.8) |
5.5 | 1.2 | 5.3 | 1.3 | 5.5 | 1.4 |
Creatinine (mg/dL) (0.51 – 0.95) |
0.86 | 0.14 | 0.82 | 0.15 ** | 0.85 | 0.15 # |
RBC (M/uL) (3.93 – 5.22) |
4.6 | 0.4 | 4.6 | 0.4 | 4.6 | 0.4 |
WBC (K/uL) (3.98 – 10.04) |
5.7 | 1.5 | 5.4 | 1.8 | 5.1 | 1.3 * |
Glucose (mg/dL) (74 - 99) |
92 | 7.5 | 94.2 | 9 * | 92.8 | 12.7 |
HbA1C (%) (4 - 6) |
4.9 | 0.4 | 5 | 0.5 | 5 | 0.4 |
Insulin (μU/mL) (2.6 – 24.9) |
7.1 | 3.3 | 8.6 | 3.5 ** | 9.6 | 4.7 *** |
HOMA IR | 2 | 1.09- 2.40 | 2.4 | 1.11- 2.95 | 1.8 | 1.08-2.44 |
Vascular parameters | ||||||
L-ABI | 1.03 | 0.09 | 1 | 0.09 * | 1.03 | 0.09 # |
R-ABI | 1.05 | 0.07 | 1.02 | 0.07 * | 1.04 | 0.08 |
L-CAVI | 6.5 | 1.1 | 6.4 | 1 | 6.6 | 1.1 |
R-CAVI | 6.6 | 1.1 | 6.5 | 1 | 6.6 | 1.1 |
Systolic BP (mmHg) (120 - 140) |
117.7 | 12.6 | 114.7 | 9.1 | 115.9 | 9.7 |
Diastolic BP (mmHg) (80 - 90) |
69.5 | 8.8 | 68 | 10.1 | 67.4 | 7.6 |
Heart rate (bpm) | 67.7 | 11.8 | 66.1 | 9.3 | 69.5 | 13 |
hsCRP: high-sensitivity C-reactive protein; AST: aspartate aminotransferase; ALT: alanine aminotransferase; TSH: thyroid-stimulating hormone; RBC: red blood cells; WBC: white blood cells; HbA1C: hemoglobin A1c; HOMA-IR: homeostatic model assessment of insulin resistance; L-ABI: left ankle-brachial index; R-ABI: right ankle-brachial index; L-CAVI: left cardio-ankle vascular index; R-CAVI: right cardio-ankle vascular index; BP: blood pressure. Brackets indicate clinical reference ranges. Data represented as mean ± SD (n = 30) or interquartile range (IQR) for parametric and non-parametric variables respectively.
P <0.05
P <0.01
P <0.001 compared with baseline
P <0.05 compared with control oil intervention.