Skip to main content
. 2021 Jun 23;40(3):89–100. doi: 10.1089/mab.2021.0024

Table 1.

Structure of Common Tumor-Associated Carbohydrate Antigens

Tumor-associated carbohydrate antigens Structure
Tn GalNAcSer/Thr
sialyl Tn Neu5Acα2-6GalNAcaSer/Thr
T antigen Galβ1-3GalNAcα1-Ser/Thr
Globo-H Fucα1-2Galβ1-3GalNAcβ1-3Galα1-4Galβ1-4Glc
LeY Fuc(α1 → 2)Gal(β1 → 4)[Fuc(α1 → 3)]GlcNAc
SLea Neu5Acα2,3Galβ1,3(Fucα1,4)GlcNAc
SLeX Neu5Acα2,3Galβ1,4 (Fucα1,3)GlcNAc
GM3 Neu5Acα2,3Galβ1,4Glcβ1Cer
GD3 Neu5Acα2,8Neu5Acα2,3Galβ1, 4Glcβ1Cer
GD2 GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1, 4Glcβ1Cer

LeY, Lewis Y; SLea, sialyl Lewis A; SLeX, sialyl Lewis X; STn, sialyl Tn.