Table 1.
Tumor-associated carbohydrate antigens | Structure |
---|---|
Tn | GalNAcSer/Thr |
sialyl Tn | Neu5Acα2-6GalNAcaSer/Thr |
T antigen | Galβ1-3GalNAcα1-Ser/Thr |
Globo-H | Fucα1-2Galβ1-3GalNAcβ1-3Galα1-4Galβ1-4Glc |
LeY | Fuc(α1 → 2)Gal(β1 → 4)[Fuc(α1 → 3)]GlcNAc |
SLea | Neu5Acα2,3Galβ1,3(Fucα1,4)GlcNAc |
SLeX | Neu5Acα2,3Galβ1,4 (Fucα1,3)GlcNAc |
GM3 | Neu5Acα2,3Galβ1,4Glcβ1Cer |
GD3 | Neu5Acα2,8Neu5Acα2,3Galβ1, 4Glcβ1Cer |
GD2 | GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1, 4Glcβ1Cer |
LeY, Lewis Y; SLea, sialyl Lewis A; SLeX, sialyl Lewis X; STn, sialyl Tn.