Figure 11.

AuNRs deliver BAG3 siRNA to silence the heat shock response and mediate photothermal therapy for cancer killing. a) Schematic illustration of the design of AuNRs–siRNA in the improved photothermal therapy platform. b) Expression of BAG3 mRNA in Cal-27 cells treated with AuNRs–siRNA after laser irradiation; “+” indicates with, and “−” indicates without. c) Average growth percentage of tumors from different groups (G1–G5) in the xenograft model measured every other day after the AuNRs–siRNA and laser irradiation treatment. Reproduced with permission.^[224] Copyright 2016, Elsevier.