Table 4.
The remarkably enriched GO terms for these DEGs
| Ontology | ID | Description | Counta | adj. P | Gene ID |
|---|---|---|---|---|---|
| CC | GO:0005911 | Cell–cell junction | 12 | 6.95E−05 | PERP/PPL/EPCAM/FAT1/CLDN1/BAIAP2L1/DSG2/CLDN7/CLDN12/PTPRK/CGN/PDLIM3 |
| MF | GO:0050839 | Cell adhesion molecule binding | 11 | 0.002369034 | SFRP2/PPL/SPP1/EPCAM/OLFM4/BAIAP2L1/TSPAN8/DSG2/CCN2/PROM1/CGN |
| CC | GO:0045177 | Apical part of cell | 9 | 0.002472218 | EPCAM/FAT1/CLDN1/MYO6/MUC1/DSG2/KCNK1/PROM1/MAL2 |
| CC | GO:0016324 | Apical plasma membrane | 8 | 0.002817074 | EPCAM/FAT1/CLDN1/MUC1/DSG2/KCNK1/PROM1/MAL2 |
| CC | GO:0016328 | Lateral plasma membrane | 4 | 0.003551437 | EPCAM/CLDN1/DSG2/CLDN12 |
| CC | GO:0030057 | Desmosome | 3 | 0.004170446 | PERP/PPL/DSG2 |
| CC | GO:0005923 | Bicellular tight junction | 5 | 0.004170446 | EPCAM/CLDN1/CLDN7/CLDN12/CGN |
| CC | GO:0070160 | Tight junction | 5 | 0.004305753 | EPCAM/CLDN1/CLDN7/CLDN12/CGN |
| BP | GO:0030198 | Extracellular matrix organization | 10 | 0.006175832 | MMP7/SFRP2/SOX9/SPP1/PLOD2/MFAP2/ELF3/CCN2/SPINT2/CCDC80 |
| CC | GO:0043296 | Apical junction complex | 5 | 0.006294613 | EPCAM/CLDN1/CLDN7/CLDN12/CGN |
| BP | GO:0043062 | Extracellular structure organization | 10 | 0.010219773 | MMP7/SFRP2/SOX9/SPP1/PLOD2/MFAP2/ELF3/CCN2/SPINT2/CCDC80 |
| BP | GO:0098742 | Cell–cell adhesion via plasma-membrane adhesion molecules | 8 | 0.011695026 | ANXA3/EPCAM/FAT1/CLDN1/DSG2/CLDN7/CLDN12/PCDHB16 |
| CC | GO:0005884 | Actin filament | 4 | 0.020148378 | PLS3/MYO6/PLS1/PDLIM3 |
| MF | GO:0001968 | Fibronectin binding | 3 | 0.023328786 | SFRP2/CCN2/CCDC80 |
| CC | GO:0062023 | Collagen-containing extracellular matrix | 7 | 0.023568462 | SFRP2/LGALS4/ASPN/MFAP2/CCN2/F3/CCDC80 |
| MF | GO:0003779 | Actin binding | 8 | 0.042702752 | PLS3/BAIAP2L1/MYO6/PLS1/ENC1/CGN/MLPH/PDLIM3 |
| MF | GO:0002162 | Dystroglycan binding | 2 | 0.044071511 | AGR2/AGR3 |
| BP | GO:0016338 | Calcium-independent cell–cell adhesion via plasma membrane cell-adhesion molecules | 3 | 0.047603714 | CLDN1/CLDN7/CLDN12 |
BP biological processes, CC cellular component, MF molecular functions
aThe “Count” refers to the numbers of DEGs that were enriched in the corresponding functional category