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. 2021 Jul 21;11:677826. doi: 10.3389/fonc.2021.677826

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Copyright © 2021 Liu, Wang, Wang, Li, Yang, Yan, Yang, Ma, Gao, Guan, Yi, Xia, Li and Wu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RBM10 is highly mutated in early-stage LUAD. (A) The mutational frequency of RBM10 in the TCGA_LUAD, CHOICE_ADC and GGN cohorts. (B, C) RBM10 mutation rate is significantly higher in GGN cohort than those in the TCGA_LUAD (B) and CHOICE_ADC (C) cohorts. (D) RBM10 deficiency leads to shorter overall survival in LUAD.