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METTL14 attenuates MAVS protein expression. A) Immunoblot analysis of the main adaptors in RLRs signaling pathway in Mettl14 +/+ and Mettl14 +/− peritoneal macrophages infected with SeV or EMCV for the indicated times. B,C) Immunoblot analysis (B) and quantification (C) of innate main adaptors degradation kinetics in Mettl14 +/+ and Mettl14 +/− peritoneal macrophages treated with the protein synthesis inhibitor CHX for the indicated times.
