Table 3.

Summary of HER2 fluorescence in situ hybridization results and ERBB2 assessment by next-generation sequencing from matched tumor block and HER2 fluorescence in situ hybridization results of alternate tumor block from 13 patients.

Study Patient	HER2 FISH result, matched block	ERBB2 Status by NGS, matched block	HER2 FISH result, alternate sample(s)
1	Group 2	Amplified	Group 1
2	Group 2	Amplified	Group 1
3	Group 2	Nonamplified	Group 5
4	Group 3	Nonamplified	Group 5
5	Group 3	Amplified	Group 5
6	Group 4	Nonamplified	Group 4
7	Group 4	Nonamplified	Group 4
8	Group 4	Nonamplified	Group 4
9	Group 4	Nonamplified	Group 4
10	Group 4	Nonamplified	Group 4
11	Group 4	Nonamplified	Group 4, Group 5
12	Group 4	Nonamplified	Group 5, Group 5
13	Group 4	Copy number gain	Group 1

Abbreviations: FISH, fluorescence in situ hybridization; HER2, human epidermal growth factor receptor 2; NGS, next-generation sequencing