Table 2.
Factors associated with attrition in TB‐index participants
| Univariable analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
| Variable | Crude hazard ratio | (95% confidence interval) | p‐value | Adjusted hazard ratio | (95% confidence interval) | p‐value |
| Age a | 0.99 | (0.96 to 1.01) | 0.297 | 0.98 | (0.95 to 1.01) | 0.149 |
| Male sex | 1.42 | (0.77 to 2.62) | 0.261 | 2.18 | (1.10 to 4.34) | 0.026 |
| Severe anaemia (Hb <8 g/dL) | 2.23 | (1.20 to 4.18) | 0.012 | 2.01 | (0.97 to 4.17) | 0.062 |
| Renal insufficiency (eGFR < 60 mL/min) | 1.13 | (0.55 to 2.32) | 0.732 | – | – | |
| CrAg positivity | 0.65 | (0.15 to 2.75) | 0.558 | 0.55 | (0.12 to 2.55) | 0.446 |
| TB‐LAM positivity | 1.94 | (1.05 to 3.60) | 0.035 | 1.38 | (0.67 to 2.85) | 0.383 |
| Cotrimoxazole preventive therapy | 0.36 | (0.05 to 2.70) | 0.323 | – | – | – |
| Low CD4 (<200 cells/μL) | 1.96 | (0.81 to 4.74) | 0.133 | 1.72 | (0.65 to 4.52) | 0.271 |
| Suboptimal adherence versus ART initiated | 1.72 | (0.94 to 3.14) | 0.077 | – | – | |
Cox regression, crude model (left) and adjusted model (right). Number of subjects = 124. eGFR, Estimated creatinine glomerular filtration rate GFR (CKD‐EPI formula).
a
Per unit increase.