Table 2. Summary of imaging findings and analysis of their difference in relation to tumor type using Fisher’s exact test.
Imaging findings | DMG n (%) | mGBM-H3wt n (%) | p-value | |
---|---|---|---|---|
Location | thalamus | 9/24 (37.5) | 0.129 | 0.095 |
brainstem | 12/24 (50) | 0.351 | 0.224 | |
spinal cord | 3/24 (12.5) | 0.618 | 0.417 | |
Edema present | 6/24 (25) | 15/19 (79) | 0.001 | |
Rim enhancement | 10/24 (42) | 13/19 (68) | 0.125 | |
Tumor necrosis | 17/24 (71) | 17/19 (89) | 0.257 | |
Strong enhancement | 3/24 (12.5) | 11/19 (58) | 0.003 | |
Low enhancement | 12/24 (50) | 3/19 (16) | 0.026 | |
Mass effect | 24/24 (100) | 19/19 (100) | ||
Multifocal lesions | 0 | 3/19 (16) |
DMG: Diffuse midline glioma, H3 K27M-mutant; mGBM-H3wt: Glioblastoma of the midline structures without H3F3A/HIST1H3B mutations.