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. 2021 Aug 4;16(8):e0249647. doi: 10.1371/journal.pone.0249647

Table 3. Analysis of peritumoral edema and strong contrast enhancement using logistic regression models.

Variables n (% with edema/strong contrast enhancement) Odds ratio 95%-confidence interval p-value
Peritumoral edema
Tumor type mGBM-H3wt 15/19 (79) REF.
DMG 6/24 (25) 0.13 [0.02–0.62] 0.010
MVP No 1/9 (11) REF.
Yes 20/34 (59) 4.00 [0.38–41.51] 0.246
Strong Contrast enhancement
Tumor type mGBM-H3wt 10/19 (53) REF.
DMG 3/24 (12.5) 0.10 [0.02–0.47] 0.003

DMG: Diffuse midline glioma, H3 K27M-mutant; mGBM-H3wt: Glioblastoma of the midline structures without H3F3A/HIST1H3B mutations; REF.: Reference group; MVP: Microvascular proliferations.