Table 2. Univariate comparison between the patients who relapsed and those who maintained remission.
| Remission | Relapse | Odds ratio | 95% CI | p value | |
|---|---|---|---|---|---|
| Total number of patients | 52 (74.3%) | 18 (25.7%) | |||
| Male gender | 31 (44.3) | 12 (17.1%) | 0.74 | 0.24–2.28 | 0.78 |
| Age, years | 44 (21–81) | 44 (20–76) | 0.989 | ||
| Age at diagnosis, years | 35 (17–78) | 34.5 (21–66) | 0.682 | ||
| Duration of disease, years | 3 (0–37) | 6 (0–28) | 0.184 | ||
| Duration of disease remission, years | 1 (0–10) | 1 (0–9) | 0.594 | ||
| Extension of disease | |||||
| Pancolitis | 23 (32.9%) | 5 (7.1%) | 0.41 | 0.11–1.49 | 0.207 |
| Left-side colitis | 14 (20.0%) | 5 (7.1%) | 0.67 | 0.18–2.54 | 0.739 |
| Proctitis | 15 (21.4%) | 8 (11.4%) | Reference | ||
| Partial mayo score:1 | 4 (5.7%) | 1 (1.4%) | 0.71 | 0.074–6.77 | 1 |
| Type of oral 5-ASA | |||||
| Pentasa | 32 (45.7%) | 11 (15.7%) | 1.02 | 0.34–3.05 | 1 |
| Asacol | 20 (28.6%) | 7 (10.0%) | Reference | ||
| White blood cell count, 103/μl | 5.7 (3.7–11.3) | 5.6 (4.5–14.2) | 0.31 | ||
| Hemoglobin, g/dl | 13.95 (9.7–16.5) | 14.5 (8.9–16.7) | 0.377 | ||
| Platelet, 103/μl | 225 (115–553) | 216.5 (147–354) | 0.895 | ||
| Albumin, g/dl | 4.4 (3.7–5.2) | 4.5 (3.9–5) | 0.239 | ||
| C-reactive protein ≥ 3mg/L | 4 (5.7%) | 1 (1.4%) | 0.69 | 0.71–6.62 | 1 |
| History | |||||
| Thiopurines use | 1 (1.4%) | 2 (2.9%) | 6.38 | 0.54–75.01 | 0.16 |
| Corticosteroids use | 8 (11.4%) | 8 (11.4%) | 4.4 | 1.33–14.55 | 0.02 |
| Acute severe ulcerative colitis | 2 (2.9%) | 7 (10.0%) | 15.91 | 2.90–87.23 | 0.001 |