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. 2021 Jul 23;10:e68812. doi: 10.7554/eLife.68812

Table 3. Age- and sex-stratified adjusted hazard ratios of time to symptomatic malaria.

Comparison Age aHR (95% CI) Sex aHR (95% CI)
<5 years 5 to 15 years >15 years Male Female
1-Month main model 3.77 (2.02,7.04) 2.45 (1.79,3.35) 2.55 (1.57,4.15) 1.76 (1.24,2.50) 3.71 (2.62,5.24)
1-Month pre-symptomatic 2.85 (1.19,6.79) 1.61 (1.05,2.46) 1.90 (0.93,3.86) 1.24 (0.75,2.05) 2.34 (1.47,3.71)
3-Month main model 2.47 (1.59,3.84) 1.49 (1.21,1.85) 1.69 (1.23,2.32) 1.29 (1.01,1.64) 2.03 (1.62,2.55)
3-Month pre-symptomatic 2.00 (1.20,3.34) 1.16 (0.90,1.48) 1.35 (0.94,1.93) 1.05 (0.79,1.39) 1.52 (1.18,1.97)
6-Month main model 1.94 (1.34,2.80) 1.32 (1.11,1.57) 1.31 (1.01,1.70) 1.13 (0.93,1.39) 1.62 (1.35,1.94)
6-Month pre-symptomatic 1.63 (1.08,2.46) 1.11 (0.92,1.34) 1.10 (0.83,1.46) 0.98 (0.78,1.22) 1.33 (1.09,1.62)
12-Month main model Not calculated* Not calculated* Not calculated* 1.10 (0.86,1.19) 1.21 (1.05,1.41)
12-Month pre-symptomatic 1.24 (0.88,1.74) 1.00 (0.86,1.17) 0.85 (0.68,1.07) 0.91 (0.77,1.09) 1.04 (0.88,1.22)
29-Month main model 1.38 (1.05,1.81) 1.16 (1.02,1.32) 0.96 (0.81,1.13) 1.08 (0.94,1.24) 1.14 (1.01,1.30)
29-Month pre-symptomatic 1.23 (0.92,1.64) 1.06 (0.93,1.21) 0.88 (0.74,1.05) Not calculated* Not calculated*

Abbreviations: CI, confidence interval; aHR, adjusted hazard ratio.

*Not calculated due to data sparsity.

Statistically significant effect measure modification by the log-likelihood ratio test is bolded.