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. 2021 Jul 27;2021:6366254. doi: 10.1155/2021/6366254

Figure 2.

Figure 2

miR-146a protects NRCMs from H/R-induced oxidative stress. (a, b) NRCMs were transfected with the miR-146a mimic and subjected to H/R injury. (a) ROS level detected by the 2′,7′-dichlorofluorescin diacetate probe and MD level in each group (n = 6). (b) MnSOD and NADPH oxidase activity in cells (n = 6). ∗P < 0.05vs. vehicle-CON; #P < 0.05vs. vehicle-H/R. (c, d) NRCMs were transfected with the miR-146a inhibitor and subjected to H/R injury. (c) ROS level detected by the 2′,7′-dichlorofluorescin diacetate probe and MD level in each group (n = 6). (d) MnSOD and NADPH oxidase activity in cells (n = 6). ∗P < 0.05vs. vehicle-CON; #P < 0.05vs. vehicle-H/R. Cell experiments were repeated for 3 times. Two-way analysis of variance followed by Tukey's post hoc test was used.