Table 2.
Distribution of (pro)renin receptor expression in organs outside the brain.
| Case 1 | Case 2 | Case 3 | |
|---|---|---|---|
| Thyroid | |||
| Follicular epithelial cell | + | − | + |
| Lymph duct | − | − | − |
|
| |||
| Lung | |||
| Alveoli epithelial cell | − | − | − |
| Blood vessel | − | − | − |
|
| |||
| Liver | |||
| Hepatic cell | + | + | + |
| Epithelial cell | − | − | − |
| Cholangioepithelial cell | − | − | − |
| Blood vessel | − | − | − |
| Lymph duct | − | − | − |
|
| |||
| Pancreas | |||
| Acinar cell | − | − | − |
| Pancreatic duct epithelial cell | − | − | + |
| Islets of Langerhans | − | − | − |
| Blood vessel | − | − | − |
| Lymph duct | − | − | − |
|
| |||
| Adrenal gland | |||
| Zona glomerulosa | + | − | + |
| Zona fasciculate | − | − | − |
| Zona reticularis | − | − | ± |
| Medulla | + | − | + |
|
| |||
| Kidney | |||
| Glomerulus | − | − | − |
| Proximal tubule | − | + | + |
| Distal tubule | ± | + | + |
| Collecting duct | + | + | + |
| Blood vessel | − | − | − |
| Lymph duct | − | − | − |
|
| |||
| Skeletal muscle | |||
| Lingual muscle | N/A | − | + |
| Diaphragm | + | N/A | + |
| Iliopsoas muscle | N/A | N/A | ± |
| Cardiomyocytes | + | + | + |
|
| |||
| Smooth muscle | |||
| Aorta | N/A | − | + |
| Colon | ± | − | − |
The immunostaining intensity in the cytoplasm was evaluated on a scale of − (no staining), ± (borderline staining), and + (positive staining). N/A, not available.