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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Cancer Res. 2021 Mar 16;81(15):4145–4154. doi: 10.1158/0008-5472.CAN-20-3822

Table 1:

Trastuzumab/T-DM1 Plasma AUCs with and without 1HE

Dose Group AUClast (day×nM) AUClast with 1HE (day×nM) P-value
Trastuzumab 0.1 mg/kg 33.18 ±5.071 26.83 ±3.96 0.06
Trastuzumab 1 mg/kg 302.9 ±37.45 295.6 ±98.89 0.88
T-DM1 1.8 mg/kg 479.7 ±40.08 450.3 ±71.31 0.44
Trastuzumab 10 mg/kg 3077 ±121.2 3133 ±239.7 0.66