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. 2021 May 21;14(8):767–778. doi: 10.1158/1940-6207.CAPR-20-0607

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©2021 The Authors; Published by the American Association for Cancer Research

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Figure 5. Local delivery of anti–PD-1 increases STING protein levels in low- and high-grade lesions. Representative IHC images of STING expression in oral lesions. A, significant difference of STING expression was detected between untreated and PD-1 treated mice groups. Immunostaining signal was defined as the number of positive cells per mm2. Right graphs: **, P <0.01; ***, P < 0.001; ****, P < 0.0001. Scale bar, 50 μm. — Local delivery of anti–PD-1 increases STING protein levels in low- and high-grade lesions. Representative IHC images of STING expression in oral lesions. A, significant difference of STING expression was detected between untreated and PD-1 treated mice groups. Immunostaining signal was defined as the number of positive cells per mm². Right graphs: **, P <0.01; ***, P < 0.001; ****, P < 0.0001. Scale bar, 50 μm.