Table 1.

Required sample size (per group) for between subject comparisons of mean NDI for following ROIs

	SB (NDI)		MB2 (NDI)		MB3 (NDI)		SB required N for effect size of		MB2 required N for effect size of		MB3 required N for effect size of
	MEAN	SD	MEAN	SD	MEAN	SD	5%	10%	5%	10%	5%	10%
BCC	0.643	0.028	0.572	0.021	0.549	0.022	17	6	13	5	15	5
GCC	0.635	0.020	0.569	0.020	0.552	0.023	10	4	12	4	16	5
CST	0.768	0.024	0.678	0.019	0.659	0.021	10	4	8	4	10	4
EC	0.516	0.011	0.478	0.011	0.465	0.012	6	3	6	3	7	3
OR	0.574	0.020	0.531	0.021	0.519	0.023	11	4	14	5	18	6
FL	0.450	0.017	0.423	0.018	0.408	0.017	13	5	16	5	16	5
OL	0.464	0.020	0.441	0.018	0.435	0.017	17	6	16	5	15	5
Caudate	0.532	0.013	0.488	0.013	0.467	0.015	7	3	8	3	11	4
Putamen	0.520	0.013	0.479	0.011	0.463	0.012	7	3	6	3	7	3
Thalamus	0.575	0.015	0.512	0.010	0.491	0.010	8	3	5	3	6	3
Cerebellum	0.615	0.022	0.591	0.011	0.583	0.011	12	4	5	3	5	3

BCC body of corpus callosum, GCC genu of corpus callosum, CST corticospinal tracts, EC external capsules, OR optic radiation, FL frontal lobe, OL occipital lobe, caudate, putamen, thalamus and cerebellum