Table 3.

Required sample size (per group) for between subject comparisons of mean FISO for following ROIs

	SB (FISO)		MB2 (FISO)		MB3 (FISO)		SB required N for effect size of		MB2 required N for effect size of		MB3 required N for effect size of
	MEAN	SD	MEAN	SD	MEAN	SD	5%	10%	5%	10%	5%	10%
BCC	0.221	0.025	0.196	0.020	0.173	0.021	109	28	92	24	122	32
GCC	0.234	0.021	0.215	0.023	0.210	0.022	70	19	98	26	90	24
CST	0.159	0.015	0.126	0.012	0.137	0.016	75	20	76	20	117	30
EC	0.044	0.009	0.026	0.005	0.028	0.005	385	98	315	79	220	56
OR	0.102	0.005	0.074	0.004	0.076	0.008	25	8	25	8	85	22
FL	0.204	0.049	0.188	0.047	0.160	0.045	492	124	532	135	665	167
OL	0.137	0.018	0.115	0.023	0.104	0.020	149	39	354	89	315	79
Caudate	0.228	0.019	0.219	0.018	0.210	0.016	63	17	59	16	52	14
Putamen	0.032	0.006	0.018	0.004	0.021	0.006	315	80	522	132	622	157
Thalamus	0.180	0.016	0.152	0.020	0.157	0.018	66	18	140	36	107	28
Cerebellum	0.193	0.024	0.160	0.022	0.146	0.027	135	35	166	43	279	71

BCC body of corpus callosum, GCC genu of corpus callosum, CST corticospinal tracts, EC external capsules, OR optic radiation, FL frontal lobe, OL occipital lobe, caudate, putamen, thalamus and cerebellum