Table 2.

The comparison between neurotransmitters and neuromodulators; based on Konturek S. J. Human’s Physiology

	Neurotransmitters	Neuromodulators
Most of the effect on	Postsynaptic neuron	Multiple neurons
Reabsorption	Yes	No
Time of action	Short	Long
Main receptors	Ionotropic receptors	Metabotropic receptors