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. 2021 Jul 10;48(7):5689–5697. doi: 10.1007/s11033-021-06535-2

Table 3.

The action of ginkgolides assigns to the type of neuroregulator

Action Neurotransmitter Neuromodulator References
Ginkgolides as PAF inhibitors: binding to metabotropic receptors  +  [8]
Ginkgolides as TLR4 antagonists: long-lasting regulation  +  [16]
Ginkgolides as PLA2 inhibitors: neuronal signal modulation  +   +  [38]
Ginkgolides vs glutamate: NMDA and AMPA inhibition (ionotropic receptors)  +  [20]
Ginkgolides vs GABA: Binding to GABAA and GABAC receptors (ionotropic receptors)  +  [26]
Ginkgolides influence on serotonin transmission: binding to the 5-TH3 receptors (ionotropic receptors)  +  [27]
Ginkgolides vs dopamine and noradrenaline: desensitization  +  [30]
Ginkgolides vs apoptosis: TNFR inhibition and desensitization  +  [32]
Ginkgolides as free radical scavengers: the oxidative proteins level upregulation  +  [36]