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. 2021 Aug 4;11:15782. doi: 10.1038/s41598-021-95245-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Lower ex vivo degranulation of CMV specific KIR⁺ T lymphocytes compared to KIR⁻ counterpart in HSCT recipients. Density plots illustrating the ex vivo degranulation of (A) IE1 and (B) pp65 specific KIR2DL2/3⁻ and KIR2DL2/3⁺ T lymphocytes from HSCT recipients. PBMC at day 100 post-graft were incubated with IE1 or pp65 peptivators during 6 h. T cell degranulation observed in 5 recipients against CMV with 3 specific responses against IE1 (C) and 4 specific responses against pp65 (D). Student’s t test. **Indicates p < 0.01.