Table 8.
Fraction and cumulative extraction yield for scale-up prediction and validation of 0.5 kg feed sample.
| Operating condition | Fraction | Cumulative yield, YE (% g/g sample) | Error (%) | |
|---|---|---|---|---|
| Prediction* | Validation | |||
| L1 | 1 | 1.23 | 0.78 | 36.81 |
| 2 | 1.51 | 1.48 | 2.00 | |
| 3 | 1.74 | 1.67 | 4.46 | |
| 4 | 5.37 | 3.05 | 43.18 | |
| 5 | 16.81 | 14.58 | 13.26 | |
| 6 | 19.68 | 17.63 | 10.40 | |
| 7 | 20.47 | 19.04 | 6.99 | |
| 8 | 20.48 | 19.43 | 5.13 | |
| AARD OEC (%) | 4.44 | 13.90 | – | |
| L2 | 1 | 1.81 | 1.59 | 12.50 |
| 2 | 3.81 | 3.07 | 19.59 | |
| 3 | 13.35 | 6.46 | 51.63 | |
| 4 | 19.69 | 16.37 | 16.88 | |
| 5 | 22.53 | 20.67 | 8.28 | |
| 6 | 23.20 | 23.14 | 0.28 | |
| 7 | 23.39 | 23.77 | 1.59 | |
| 8 | 23.45 | 24.13 | 2.92 | |
| AARD OEC (%) | 6.13 | 14.21 | – | |
L1: P = 200 bar, T = 60 °C, co-solvent = 50% ethanol–water with 10% (v/v) concentration, L2: P = 262 bar, T = 80 °C, co-solvent = 30% ethanol–water with 13% (v/v) concentration.
*Prediction data were obtained from previous study32.