. 2021 Aug 4;11:15770. doi: 10.1038/s41598-021-95353-4

Table 5.

PCR analysis of the heart. mRNAs were measured from the heart of offspring following 12-weeks of the indicated diet (LF, HF, HFB).

Gene	LEAN	LEAN	LEAN	GDM	GDM	GDM
Gene	LF	HF	HFB	LF	HF	HFB
CL synthesis
TAZ	1.00 ± 0.09^b	1.38 ± 0.11^a	0.87 ± 0.05^b	1.16 ± 0.08^a,b	1.19 ± 0.10^a	1.28 ± 0.05^a
PGS	1.00 ± 0.21^b	1.38 ± 0.05^a	0.90 ± 0.10^b	1.13 ± 0.13^a,b	1.40 ± 0.15^a	1.06 ± 0.08^b
PTPMTI	1.00 ± 0.10	1.00 ± 0.09	0.92 ± 0.04	1.00 ± 0.22	1.15 ± 16	1.10 ± 0.24
FAO
PGC1α	1.00 ± 0.14^b	1.12 ± 0.09^b	1.02 ± 0.12^b	1.79 ± 0.21^a	1.62 ± 0.18^a	1.46 ± 0.15^a
SIRT1	1.00 ± 0.15	0.91 ± 0.07	0.79 ± 0.04	1.05 ± 0.22	0.82 ± 0.06	1.14 ± 0.10
CPT1β	1.00 ± 0.16^a,b	1.16 ± 0.19^a,b	0.83 ± 0.15^b	1.06 ± 0.22^a,b	1.51 ± 0.17^a	1.52 ± 0.22^a
ACOX1	1.00 ± 0.23^a,b	0.37 ± 0.10^b	1.45 ± 0.28^a	1.10 ± 0.32^a,b	1.13 ± 0.28^a,b	1.40 ± 0.31^a
FA uptake
CD36	1.00 ± 0.10^a	0.50 ± 0.06^b	0.54 ± 0.09^b	1.37 ± 0.14^a	0.65 ± 0.07^b	1.02 ± 0.14^a
FABP1	1.00 ± 0.14^a	0.52 ± 0.05^b	0.50 ± 0.08^b	0.63 ± 0.10^b	0.64 ± 0.04^b	1.00 ± 0.19^a
ETC
NDUF (I)	1.00 ± 0.10^a	0.67 ± 0.04^b	0.70 ± 0.09^b	1.15 ± 0.18^a	0.84 ± 0.08^a,b	1.01 ± 0.17^a
SDHD (II)	1.00 ± 0.20^a	0.78 ± 0.06^a,b	0.54 ± 0.09^b	0.90 ± 0.24^a,b	0.61 ± 0.09^b	1.24 ± 0.18^a
COX5β (IV)	1.00 ± 0.08	1.27 ± 0.06	1.02 ± 0.10	1.20 ± 0.14	1.30 ± 0.15	1.26 ± 0.16
ATP5i (V)	1.00 ± 0.12	1.11 ± 0.09	0.96 ± 0.13	1.05 ± 0.22	1.16 ± 0.12	1.15 ± 0.27

Values are means ± SEMs (n = 7), means without a common letter differ, p < 0.05.

TAZ tafazzin, PGS phosphatidylglycerolphosphate synthase, PTPMT protein tyrosine phosphatase mitochondrial 1, PGC1α peroxisome proliferator-activated receptor gamma coactivator 1α, SIRT1 sirtuin 1, CPT1β carnitine palmitoyltransferase 1, SREBP1 sterol regulatory element-binding protein 1, ACOX1 acyl-CoA oxidase, FABP fatty acid binding protein, NDUF NADH dehydrogenase oxidoreductase core subunit S3, SDHD succinate dehydrogenase complex subunit D, COX5β cytochrome c oxidase subunit 5β, ATP5i ATP synthase subunit 5i.