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. 2021 Jul 9:1–7. doi: 10.1159/000517075

Table 2.

Influencing factors for delayed treatment

Characteristics ONT
p value
≤4.5 h, n = 80 >4.5 h, n = 172
Age, yr, mean 67.5±12.2 70.1±11.8 0.134
Male gender, n (%) 51 (63.8) 106 (61.6) 0.736
Education, n (%)
 Elementary education 15 (18.4) 64 (37.2)
 Secondary education 46 (57.5) 94 (54.7) 0.018
 Higher education 19 (24.1) 14 (8.1)
Solitary, n (%) 21 (26.3) 58 (33.7) 0.044
Residence, n (%)
 Urban 59 (73.7) 105 (61.0)
 Rural 21 (26.3) 67 (39.0) <0.001
Onset in daytime (6:00–18:00) 58 (72.5) 77 (44.8) <0.001
Etiology of ischemic stroke, n (%)
 Large artery atherosclerosis 33 (41.3) 64 (37.2)
 Small artery occlusion 26 (32.5) 70 (40.7)
 Cardioembolism 20 (25.0) 29 (16.9) 0.011
 Other demonstrated cause 0 4 (2.3)
 Undetermined cause 1 (1.2) 5 (2.9)
NIHSS at admission, median (IQR) 8 (3–14) 3 (2–7) 0.031
Stroke history, n (%) 19 (24.1) 36 (21.1) 0.523
Hypertension, n (%) 53 (66.3) 107 (62.2) 0.278
Diabetes, n (%) 36 (45.0) 70 (40.7) 0.298
Hyperlipidemia, n (%) 25 (31.3) 56 (32.6) 0.776
Atrial fibrillation, n (%) 12 (15.0) 23 (13.3) 0.165
Coronary heart disease, n (%) 12 (15.0) 27 (15.7) 0.679
Current smoker, n (%) 36 (45.0) 72 (42.0) 0.108
Regular drinker, n (%) 32 (40.0) 63 (36.7) 0.182
Self-management after onset, n (%) 8 (10.0) 118 (68.6) <0.001
Transported by ambulance, n (%) 38 (43.7) 57 (33.1) 0.018
Post-COVID-19 period, n (%) 22 (27.5) 69 (38.9) 0.015

IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; ONT, onset-to needle time.