Table 2.

Contributing factors to each endoscopic phenotype of the J pouch (multivariable analysis)

Phenotype	N	Variables	Odds ratio (95% CI)	P-value
Afferent limb involvement	131	BMI ≥ 25	1.84 (1.11–3.03)	0.017
		Hand-sewn anastomosis	1.96 (1.15–3.33)	0.013
Inlet involvement	178	Male	1.58 (1.05–2.38)	0.028
		Age at diagnosis ≥ 18 years old	0.58 (0.33–1.04)	0.068
		Age at colectomy ≥ 18 years old	0.52 (0.22–1.21)	0.13
Diffuse inflammation of the pouch body	118	Disease extent E3	2.40 (1.02–5.66)	0.045
		Preoperative anti-TNFα drugs	1.79 (1.08–2.97)	0.023
		Family history of IBD	0.67 (0.38–1.20)	0.18
		Age at diagnosis ≥ 18 years old	0.62 (0.34–1.12)	0.11
		Male	1.55 (0.92–2.61)	0.10
Focal inflammation of the pouch body	218	Disease extent E3	0.52 (0.27–0.98)	0.044
		Age at diagnosis ≥ 18 years old	1.40 (0.82–2.39)	0.22
		Preoperative immunomodulators	1.39 (0.89–2.18)	0.15
Cuffitis	192	Stapled anastomosis	2.59 (1.28–5.22)	0.008
		Preoperative CDI	2.06 (1.09–3.89)	0.025
		3-stage IPAA	1.50 (0.83–2.70)	0.18
		Dysplasia/Cancer (Indication of surgery)	0.78 (0.31–1.96)	0.59
		Preoperative anti-TNFα drugs	1.42 (0.81–2.47)	0.22
		Caucasian	0.46 (0.19–1.09)	0.076
		Male	1.51 (0.90–2.51)	0.12
Fistulas	78	Preoperative diagnosis of Crohn’s disease	10.4 (1.81–60.0)	0.009
		Family history of IBD	1.54 (0.90–2.64)	0.12
		Preoperative anti-TNFα drugs	0.63 (0.37–1.07)	0.085