. 2021 Jul 22;12:690539. doi: 10.3389/fpsyg.2021.690539

TABLE 3.

Anxiety, depression and health-related quality of life at study time points (Intention-to-treat analysis, n = 18).

	Within-group effect								Between-group effect (time × group)
	T0		T1^a		ES	T2^a		ES	T1-T0^b		T2-T0^b		F	p	ES
	Mean	SD	Mean	SD	d	Mean	SD	d	Mean	SE	Mean	SE			Partial η²
BAI													3.38	0.06	0.31
I-BMS	8.44	4.56	3.33**	2.96	–1.33	3.78*	3.15	–1.13	−5.11*	1.37	–4.67	1.40
Control	5.11	4.96	4.44	5.41	–0.13	3.33*	4.87	–0.36	–0.67	1.37	–1.78	1.40
BDI													8.04	0.00	0.52
I-BMS	13.11	8.43	3.89***	3.72	–1.24	4.11**	3.18	–1.40	−9.22**	1.79	–9.00	2.19
Control	10.44	7.11	9.22	6.12	–0.17	8.00*	6.31	–0.35	–1.22	1.79	–2.44	2.19
Health Related Quality of Life (PCOSQ)
Total													10.32	0.00	0.58
I-BMS	150.44	19.88	170.33**	19.27	1.02	174.78**	24.29	1.08	19.89***	5.09	24.33*	6.79
Control	131.78	29.64	118.11**	27.57	–0.47	134.67	33.68	–0.09	–13.67	5.09	2.89	6.79
Hirsutism													2.64	0.10	0.26
I-BMS	32.00	2.78	33.33	2.06	0.51	33.89	2.21	0.75	1.33*	1.55	1.89*	1.59
Control	27.22	7.93	23.56	10.21	–0.38	26.00	9.50	0.14	–3.67	1.55	–1.22	1.59
Acne													3.06	0.08	0.29
I-BMS	24.78	3.46	26.22	2.91	0.45	26.44	2.79	0.52	1.44*	1.19	1.67*	1.22
Control	18.00	8.99	15.67	7.50	–0.26	17.89	8.09	–0.01	–2.33	1.19	–0.11	1.22
Obese													2.38	0.13	0.24
I-BMS	24.22	10.85	28.33	8.44	0.40	28.00*	9.14	0.34	4.11*	1.67	3.78	1.31
Control	19.00	8.00	18.00	7.53	–0.13	20.89	10.03	0.18	–1.00	1.66	1.89	1.31
Infertile													1.39	0.28	0.16
I-BMS	9.89	4.86	11.56	3.25	0.39	13.67	4.80	0.78	1.67	1.18	3.78	1.44
Control	11.11	5.16	10.33	4.64	–0.15	11.67	4.74	0.11	–0.78	1.18	0.56	1.44
Menstrual													1.07	0.37	0.13
I-BMS	25.44	4.75	28.44	6.54	0.43	29.11	4.26	0.75	3.00	2.15	3.67	1.76
Control	21.89	6.09	20.67	5.79	–0.20	22.56	5.22	0.11	–1.22	2.15	0.67	1.76
Emotion													5.88	0.01	0.44
I-BMS	34.11	11.33	42.44*	5.00	0.82	43.67*	8.52	0.94	8.33**	2.65	9.56	3.01
Control	34.56	10.68	29.89	8.36	–0.46	35.67	11.68	0.10	–4.67	2.65	1.11	3.01

BAI, Beck Anxiety Inventory; BDI, Beck Depression Inventory-II; PCOSQ, Polycystic Ovary Syndrome Questionnaire; SD, standard deviation; ES, effect size; SE, standard error. ^aWithin-group difference using paired t-test. ^bBetween-group difference using independent t-test. *p < 0.05; **p < 0.01; ***p < 0.001.