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. 2021 Apr 24;25:116–126. doi: 10.1016/j.omtn.2021.04.017

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© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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lncRNA H19 induces generation of odontoblasts

Nude mice received the injection of hDPSCs transfected with oe-NC, oe-H19, oe-LATS1, or both oe-H19 and oe-LATS1. (A) The expression of lncRNA H19 and mRNA level of LATS1 determined by quantitative real-time PCR. (B) The expressions of DSPP, EZH2, and LATS1 in dentin and dental pulp-like tissues evaluated by immunohistochemistry. n = 12. ∗p < 0.05, compared with the oe-NC group (nude mice transplanted with oe-NC-transfected hDPSCs). &p < 0.05, compared with the oe-H19 group (nude mice transplanted with hDPSCs overexpressing H19).