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lncRNA H19 controls biological behaviors of hDPSCs through the LATS1-mediated Hippo-YAP signaling pathway
lncRNA H19 recruits EZH2 to the LATS1 promoter region to induce H3K27me3, resulting in the inhibition of LATS1. The loss of LATS1 blocks the activation of the Hippo-YAP signaling pathway, thus enhancing dentin differentiation, proliferation, and migration capabilities.
