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. 2021 Jul 22;8:679030. doi: 10.3389/fmed.2021.679030

Figure 1.

Figure 1

MxA expression is increased in patients with SCD, compared to controls. MxA expression in whole blood measured by MxA Protein Human ELISA (BioVendor). (A) MxA expression in de-identified remnant samples from patients with (n = 13) or without SCD (n = 37). (B) MxA expression in patients with SCD (n = 24) and race-matched controls (n = 12) summarized in Table 1. (C) Percentage of subjects summarized in Table 1 with detectable levels of MxA. (D) MxA expression of patients with SCD (n = 24) who were not tested or tested positive (n = 4) or negative (n = 11) for SARS-CoV-2 by PCR. n.s., not significant by Kruskal Wallis test with a Dunn's post-test. *p < 0.05, ****p < 0.0001 by Mann-Whitney U-test. Bars represent the mean. Circles represent values from individual patient or control samples, and error bars represent the standard deviation.