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. 2021 Jul 22;8:687079. doi: 10.3389/fvets.2021.687079

Figure 4.

Figure 4

Linear B cell epitopes affected by amino acid variations in the S glycoproteins of SADS-CoVs CH/FJWT/2018 and GDWT-P18. (A) The amino acid sequence of predicted linear B cell epitopes are shown with red bold letters. Numbers indicate the amino acid positions relative to the full-length S glycoprotein of indicated SADS-CoVs. 3D view of epitopes in the S1 subunit and the N-terminus of S2 subunit of CH/FJWT/2018 (B) or GDWT-P18 (C). 3D structure of S glycoprotein was modeled by using I-TASER server (2022). The predicted epitopes are circled and the amino acid variations are labeled with black dot. NTD, N-terminal domain (aa 19-254); CTD, C-terminal domain (aa 275-402).