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. 2021 Jul 22;12:680884. doi: 10.3389/fmicb.2021.680884

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Copyright © 2021 Yang, Chen, Liang, Tan, Liu, Sun, Wang, Xu, Li, Zhou, Wang, Wan, Song, Li and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Multidrug-resistant Aspergillus spp. isolates collected in China from 1999 to 2019. Among 16 multidrug-resistant isolates of Aspergillus spp., six Aspergillus fumigatus isolates were cross-resistant to itraconazole (ITC) and posaconazole (POS); six A. fumigatus isolates were cross-resistant to ITC, voriconazole (VRC), and POS; one Aspergillus flavus isolate was cross-resistant to ITC and VRC; one A. flavus and one Aspergillus terreus isolate were co-resistant to ITC and amphotericin B (AMB); and one Aspergillus niger isolate was co-resistant to AMB and caspofungin (CAS).