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. 2021 Jul 22;12:714846. doi: 10.3389/fphys.2021.714846

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Copyright © 2021 Sauruk da Silva, Carla da Silveira, Bueno, Malaquias da Silva, da Silva Fonseca, Fernandes and Maria-Ferreira.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The gastrointesti nal mucosal barrier. Natural polysaccharides can contain different structural characteristics and can protect the mucosa against damage caused by chemotherapy antineoplastic treatment. The mucosal barrier contains diverse barriers (e.g., mucus layer and adherent junction proteins) that promote protection against internal and external harmful substances. A single epithelial cell layer forms the physical barrier against the entry of antigens. The lamina propria is densely populated by cells of the immune system that provide protection against damaging substances.