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. 2021 Aug 5;129:112356. doi: 10.1016/j.msec.2021.112356

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Fig. 15 — Scheme showing development steps of electrochemical biosensor for SARS-CoV-2 detection. (a) capture probes (CPs) composed of thiol modified Au@Fe₃O₄ NPs to form CP with Au@Fe₃O₄ followed by hexane-1-thiol (HT) addition to obtain premix A; rGO functionalized with the host-guest complexes (SCX8-TB) for the formation of Au@SCX8-TB-rGO, which was incubated with LP (label probe) and AP (auxiliary probe) bioconjugate to form long concatamers premix B.(b) electrochemical detection was carried out formation of CP-target-LP sandwich by incubating target viral RNA extraction-premix A with premix B [185].