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. 2021 Jul 22;11:699889. doi: 10.3389/fonc.2021.699889

Figure 5.

Figure 5

PTK7 associates with extracellular matrix organization and migration in breast cancer cells. (A) Gene Ontology (GO) was performed using DAVID: Functional Annotation Tools (https://david.ncifcrf.gov/tools.jsp) and Biological Process (BP) of PTK7 positively- and negatively-correlated genes were shown. (B) Pair-wise gene correlation of PTK7 with COL1A1, FN1, WNT5B, MMP11, MMP14 or SDC1 in breast invasive carcinoma were analyzed using GEPIA Correlation Analysis tools (http://gepia.cancer-pku.cn/detail.php?clicktag=correlation). (C) MDA-MB-231 and MDA-MB-468 cells were transduced with shNC, shPTK71 or shPTK72. Cells were stained for F-actin with TRITC-phalloidin. Pictures show the TRITC-tagged Phalloidin (red) and DAPI (purple). Presentative images are shown. Magnification, 400×; scale bars, 50 μm.