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. 2021 Jul 22;11:699889. doi: 10.3389/fonc.2021.699889

Table 2.

Molecular subtyping and clinical characteristics.

Variable Molecular subtyping
Luminal A Luminal B HER2(+) TNBC
No. of subtyping patients: n (%) 96 (100) 37 (100) 74 (100) 49 (100)
Age: Median [range] 61 [37-88] 66 [41-88] 57 [33-87] 57 [32-84]
TNM stage: n (%)
 I 21 (22.1) 7 (18.9) 16 (22.2) 12 (25)
 II 46 (48.4) 24 (64.9) 33 (45.8) 18 (37.5)
 III 28 (29.5) 6 (16.2) 23 (32.0) 18 (37.5)
Lymphatic metastasis: n (%)
 Negative 47 (51.6) 20 (58.8) 36 (50.7) 26 (53.1)
 Positive 44 (48.4) 14 (41.2) 35 (49.3) 23 (46.9)
Prognosis: n (%)
 Survival 79 (82.3) 34 (91.9) 52 (70.3) 30 (61.2)
 Death 17 (17.7) 3 (8.1) 22 (29.7) 19 (38.8)
PTK7 expression
 IHC score: Mean ± s.d. 5.06 ± 2.42 5.12 ± 2.39 6.20 ± 2.41 7.46 ± 2.68
 Low PTK7 level: n (%) 36 (37.5) 13 (35.1) 20 (27.0) 6 (12.2)
 Medium PTK7 level: n (%) 41 (42.7) 14 (37.8) 25 (33.8) 12 (24.5)
 High PTK7 level: n (%) 19 (19.8) 10 (27.0) 29 (39.2) 31 (63.3)