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. 2021 Jul;13(7):4322–4338. doi: 10.21037/jtd-20-2189

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2021 Journal of Thoracic Disease. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Scatter plots and correlations. (A) Scatter plot of the relative abundance of Betaproteobacterial class, Burkholderiales order, and Alcaligenaceae family shows positive correlations with nasal disease and total immunoglobulin E (IgE) in the high-IgE asthma (HEA) group. (B) Scatter plot of the relative abundance of Betaproteobacterial class, Burkholderiales order, and Alcaligenaceae family shows negative correlations with the dose of oral steroids and sputum eosinophils. (C) Scatter plot of the relative abundance of Betaproteobacterial class, Burkholderiales order, and Alcaligenaceae family shows positive correlations with blood eosinophils in the low-IgE asthma (LEA) group (Spearman’s rank correlation coefficient, P<0.05).