Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul;9(13):1087. doi: 10.21037/atm-21-2829

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

Identification of small molecule combination with HGF- or FH1-induced hepatocyte-like cells. (A) Representative cell morphology of hepatocyte-like cells induced from SM + HGF, SM + FH1, and GF. Scale bar =100 µM. (B) Immunofluorescent of ALB and A1AT protein expression levels at day 10 (SM-induced hepatocyte) and day 24 (GF-induced hepatocyte). Scale bar =100 µM. (C) Percentage of ALB+ A1AT+ in immunofluorescence of hepatocyte cells from three differentiation protocols. (D) qRT-PCR of hepatocyte-specific marker expressed in a small molecule with SM + HGF, SM + FH1, and GF. Undifferentiated human MSCs used as control. All data presented as the mean of at least three independent experiments *P value <0.05; **P value <0.01; ***P value <0.001. qRT-PCR, quantitative real-time PCR; SM, small molecule; GF, growth factor; HGF, hepatocyte growth factor; FH1, functional hit 1.