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. 2021 Jul;9(13):1089. doi: 10.21037/atm-21-539

Table 2. The list of clinical trials registered to United States National Library of Medicine (www.clinicaltrials.gov) for treatment of HCC patients using IRE.

Study title Phase Intervention/treatment Patient Status Results Identifier
A prospective, multi-center, clinical trial using IRE for the treatment of early-stage HCC NA Dev.: NanoKnife Low Energy Direct Current (LEDC) System 26 C 77% CR presented on 1 month biopsy-proven results NCT01078415
A prospective clinical trial using IRE for the treatment of unresectable hepatic carcinoma (HC) close to the gallbladder NA Dev.: NanoKnife 30 R No results posted NCT02332551
HC in poor liver function: safety and efficacy of IRE NA Dev.: NanoKnife LEDC System 15 R Frequent hypertension due to adrenal gland damage NCT02352935
Comparison of immunological response after MWA and IRE of HCC NA Device: MWA, NanoKnife IRE 40 W No results posted NCT03040453
A prospective clinical trial using IRE for treatment of liver cancers NA Dev.: IRE System 18 C No results posted NCT02828865
Study of the contribution of automatic image fusion of a cone-beam CT volume with ultrasound during percutaneous ablation treatment of hepatic tumors NA Rad.: interact active tracker 60 R No results posted NCT04420026
IRE of unresectable liver tumors - a phase I study of safety and feasibility NA Proc.: IRE 15 R No results posted NCT04404647
Prospective evaluation of tumor response to cancer treatment therapies Proc.: TACE, Y-90, MWA, IRE 10 T No results posted NCT02787954
Evaluation of tumor ablation effects by IRE for patients with malignant liver tumors NA Proc.: IRE 20 C No results posted NCT02010801

A, active; C, completed; R, recruiting; T, terminated; W, withdrawn; HCC, hepatocellular carcinoma; IRE, irreversible electroporation; MWA, microwave ablation; NA, not available; TACE, transarterial chemoembolization.