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. 2021 Jul;9(13):1070. doi: 10.21037/atm-21-313

Figure 3.

Figure 3

Systemic FK506 concentration comparison in Group 1: for the first iteration of NHP studies, M1 and M2, against the second iteration of NHP studies, M3 and M4. By using fewer laminated implants, systemic FK506 levels were brought to the target range for up to 11 days in vivo without requiring additional IM administration. NHP, non-human primate.