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. 2021 Jul 22;12:679897. doi: 10.3389/fimmu.2021.679897

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Copyright © 2021 Qu, Li, Xu, Zhao, Wu, Wang and Xie

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kae altered fecal metabolic composition. (A) PLS-DA analysis score plot showing comparisons of the NC vs DSS and DSS vs DSS-Kae group metabolome profiles. (B) OPLS-DA analysis score plots showing comparisons of the NC vs DSS and DSS vs DSS-Kae group metabolome profiles. (C) Heat map showing metabolites differing significantly in abundance between the DSS and DSS-Kae groups. (D) KEGG pathway analysis of the DSS and DSS-Kae groups. Statistical analysis was conducted by calculation of Pearson correlation coefficients (VIP > 1 and P < 0.05).