Skip to main content
. 2021 Jul 22;12:679897. doi: 10.3389/fimmu.2021.679897

Figure 8.

Figure 8

Transplantation of microbiota altered in response to Kae recapitulates the effects of Kae treatment on DSS-induced colitis. (A) Design of the FMT experiment on DSS-treated mice (n = 10/group). (B) Disease activity index of FMT mice during the course of colitis. (C, D) Representative images of mouse colon at sacrifice and statistical analysis of colon length data from each FMT group. (E, F) Representative images of H&E staining of colon samples (scale bar, 200 μm) and histological scores of colonic tissues. Serum inflammatory factors: (G) IL-1β, (H) IL-6, and (I) TNF-α were measured using ELISA kits. (J) Serum LPS levels indicate the endotoxemia index. Data are expressed as the mean ± SEM, n = 4–10, analyzed using one-way ANOVA with Tukey post-hoc analysis. DSS (vs. NC, # P < 0.05; ## P < 0.01; vs. DSS-Kae, *P < 0.05, **P < 0.01); F-Kae (vs. F-NC, aa P < 0.01); F-Kae (vs. F-DSS, bb P < 0.01); ns, no significant difference.