Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Kae exerts excellent anti-UC effects via gut microbiota pathways related to the LPS-TLR4-NF-κB core pathway. Kae reduces LPS levels by inhibiting the proliferation of pathogenic Gram-negative bacilli, thereby altering the metabolic profile, blocking NF-κB pathway activation, improving intestinal tight junction integrity, inhibiting pro-inflammatory factors, and increasing antioxidants, thus decreasing DSS-induced colonic inflammation.
