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Therapeutic effects of Juzentaihoto (JTT) (13-week oral administration) in a CCl4-induced cirrhosis mouse model. (A) Experimental scheme. (B) Serum levels of aspartate transaminase (AST), alanine transaminase (ALT), and albumin (ALB) on day 84. (C) Sirius Red staining of the liver tissue. Scale bar = 500 μm. (D) Sirius Red staining. (E) Quantification of hydroxyproline. n = 4 in each group. Data are presented as mean ± SD. ∗∗p < 0.01, ∗p < 0.05. Ctrl, control; ns, not significant.
