Table 4.
[TAIm]OH ionic liquid catalyzed aldol condensation reaction[a]
|
| |||||
|---|---|---|---|---|---|
|
Entry |
R |
Ketone |
Product |
Time (h) |
Conversion [%][b] |
|
1 |
H |
6 a |
7 a |
2 |
93 |
|
2 |
4‐MeO |
6 a |
7 b |
3.5 |
90 |
|
3 |
4‐NO2 |
6 a |
7 c |
1.2 |
96 |
|
4 |
4‐OH |
6 a |
7 d |
3 |
92 |
|
5 |
4‐Br |
6 a |
7 e |
2.5 |
95 |
|
6 |
H |
6 b |
7 f |
3 |
96 |
|
7 |
4‐MeO |
6 b |
7 g |
3 |
85 |
|
8 |
4‐NO2 |
6 b |
7 h |
2.5 |
95 |
|
9 |
4‐OH |
6 b |
7 i |
4 |
90 |
|
10 |
4‐Br |
6 b |
7 j |
4.5 |
92 |
[a] Reaction conditions: Aldehyde (1.0 mmol), ketone (12.0 mmol), ionic liquid (0.2 ml, 2.5 mmol OH group), room temperature, sealed tube. [b] GC analysis.