TABLE 3.
Two-way ANOVA statistics of dorsal and ventral hippocampus protein expression
| F(interaction) | n | p | F(Sex) | n | p | F(AIE) | n | p | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Glial glutamate transporter protein membrane expression | ||||||||||
| GLT-1 | ||||||||||
| DH | Synaptic | F(1, 25) = 0.06 | n = 29 | p = 0.81 | F(1, 25) = 0.08 | n = 7–8 | p = 0.38 | F(1, 25) = 5.49 | n = 7–8 | p = 0.03 |
| Extrasynaptic | F(1, 27) = 0.03 | n = 31 | p = 0.87 | F(1, 27) = 0.08 | n = 7–8 | p = 0.78 | F(1, 27) = 0.30 | n = 7–8 | p = 0.59 | |
| VH | Synaptic | F(1, 27) = 0.48 | n = 31 | p = 0.50 | F(1, 27) = 5.67 | n = 7–8 | p = 0.03 | F(1, 27) = 1–30 | n = 7–8 | p = 0.27 |
| Extrasynaptic | F(1, 26) = 0.64 | n = 30 | p = 0.43 | F(1, 26) = 0.23 | n = 7–8 | p = 0.64 | F(1, 26) = 0.13 | n = 7–8 | p = 0.72 | |
| xCT | ||||||||||
| DH | Synaptic | F(1, 27) = 0.32 | n = 30 | p = 0.58 | F(1, 27) = 2.57 | n = 7–8 | p = 0.12 | F(1, 27) = 0.19 | n = 7–8 | p = 0.67 |
| Extrasynaptic | F(1, 26) = 0.08 | n = 31 | p = 0.78 | F(1, 26) = 0.88 | n = 6–8 | p = 0.36 | F(1, 26) = 0.0001 | n = 6–8 | p = 0.99 | |
| VH | Synaptic | F(1, 26) = 3.60 | n = 30 | p = 0.07 | F(1, 26) = 0.000078 | n = 7–8 | p = 0.99 | F(1, 26) = 1.65 | n = 7–8 | p = 0.21 |
| Extrasynaptic | F(1, 27) = 0.0009 | n = 31 | p = 0.98 | F(1, 27) = 2.79 | n = 7–8 | p = 0.11 | F(1, 27) = 0.01 | n = 7–8 | p = 0.92 | |
| GLAST | ||||||||||
| DH | Synaptic | F(1, 27) = 0.75 | n = 31 | p = 0.40 | F(1, 27) = 0.002 | n = 7–8 | p = 0.97 | F(1, 27) = 0.01 | n = 7–8 | p = 0.92 |
| VH | Synaptic | F(1, 25) = 2.12 | n = 29 | p = 0.16 | F(1, 25) = 2.93 | n = 7–8 | p = 0.01 | F(1, 25) = 3.62 | n = 7–8 | p = 0.07 |
| Glial and neuronal ephrin protein membrane expression | ||||||||||
| EphA3 | ||||||||||
| DH | Synaptic | F(1, 27) = 0.22 | n = 31 | p = 0.65 | F(1, 27) = 0.41 | n = 7–8 | p = 0.53 | F(1, 27) = 0.13 | n = 7–8 | p = 0.73 |
| VH | Synaptic | F(1, 25) = 2.12 | n = 29 | p = 0.16 | F(1, 25) = 2.93 | n = 6–8 | p = 0.10 | F(1, 25) = 3.62 | n = 6–8 | p = 0.07 |
| EphA4 | ||||||||||
| DH | Synaptic | F(1, 27) = 5.42 | n = 31 | p = 0.03 | F(1, 27) = 0.06 | n = 7–8 | p = 0.81 | F(1, 27) = 0.008 | n = 7–8 | p = 0.93 |
| Extrasynaptic | F(1, 26) = 0.55 | n = 30 | p = 0.47 | F(1, 26) = 4.05 | n = 7–8 | p = 0.06 | F(1, 26) = 0.32 | n = 7–8 | p = 0.58 | |
| VH | Synaptic | F(1, 27) = 0.49 | n = 31 | p = 0.49 | F(1, 27) = 0.15 | n = 7–8 | p = 0.71 | F(1, 27) = 0.004 | n = 7–8 | p = 0.95 |
| Extrasynaptic | F(1, 26) = 0.17 | n = 30 | p = 0.69 | F(1, 26) = 0.01 | n = 7–8 | p = 0.92 | F(1, 26) = 0.08 | n = 7–8 | p = 0.78 | |
| EphB6 | ||||||||||
| DH | Synaptic | F(1, 27) = 0.04 | n = 31 | p = 0.84 | F(1, 27) = 6.01 | n = 7–8 | p = 0.02 | F(1, 27) = 0.14 | n = 7–8 | p = 0.72 |
| VH | Synaptic | F(1, 26) = 1.23 | n = 30 | p = 0.28 | F(1, 26) = 0.52 | n = 7–8 | p = 0.48 | F(1, 26) = 1.42 | n = 7–8 | p = 0.24 |
| Neuronal synaptic protein membrane expression | ||||||||||
| PSD-95 | ||||||||||
| DH | Synaptic | F(1, 25) = 5.91 | n = 29 | p = 0.02 | F(1, 25) = 4.35 | n = 6–8 | p = 0.05 | F(1, 25) = 1.98 | n = 6–8 | p = 0.17 |
| VH | Synaptic | F(1, 26) = 1.22 | n = 30 | p = 0.28 | F(1, 26) = 0.72 | n = 7–8 | p = 0.40 | F(1, 26) = 0.44 | n = 7–8 | p = 0.51 |
| GluN2A | ||||||||||
| DH | Synaptic | F(1, 26) = 1.30 | n = 30 | p = 0.26 | F(1, 26) = 5.05 | n = 6–8 | p = 0.03 | F(1, 26) = 5.68 | n = 6–8 | p = 0.03 |
| VH | Synaptic | F(1, 25) = 0.74 | n = 29 | p = 0.40 | F(1, 25) = 3.30 | n = 6–8 | p = 0.08 | F(1, 25) = 1.00 | n = 6–8 | p = 0.33 |
| GluN2B | ||||||||||
| DH | Synaptic | F(1, 25) = 0.31 | n = 29 | p = 0.58 | F(1, 25) = 0.18 | n = 7–8 | p = 0.68 | F(1, 25) = 0.97 | n = 7–8 | p = 0.34 |
| VH | Synaptic | F(1, 27) = 0.15 | n = 31 | p = 0.71 | F(1, 27) = 0.91 | n = 7–8 | p = 0.35 | F(1, 27) = 0.24 | n = 7–8 | p = 0.63 |