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. 2021 Jul 27;7(7):e07671. doi: 10.1016/j.heliyon.2021.e07671

Table 4.

Metabolic pathways in neuron cell compartment with reactions that had higher flux values in ARSA deficient bi-cellular model compared to the model with normal ARSA activity. The adjusted p-value corresponds to Fisher's exact test for genes.

Metabolic Pathway Count % Adjusted p-value
Pyrimidine metabolism 10 30,3 5,5E-9
Purine metabolism 10 30,3 3,8E-7
Lysine degradation 7 21,2 5,7E-7
Carbon metabolism 7 21,2 4,8E-5
beta-Alanine metabolism 5 15,2 4,5E-5
Pyruvate metabolism 5 15,2 1,1E-4