Table 3.
List of Top 20 differential expression of immune transcripts in 1E4 versus autochthonous model
| Transcript | Gene Sets | Probe ID | Log2 fold change | P-value |
|---|---|---|---|---|
| Glycam1-mRNA | Adhesion | NM_008134.2:124 | -9.09 | 1.34E-07 |
| Itgb4-mRNA | Adhesion, CD molecules | NM_001005608.2:3355 | 1.73 | 2.23E-07 |
| Birc5-mRNA | Apoptosis, Cell Cycle, Cytokines & Receptors | NM_009689.2:237 | 1.43 | 2.83E-07 |
| Saa1-mRNA | Adhesion, Cytokines & Receptors, Innate, Macrophage Functions | NM_009117.3:351 | -3.13 | 5.19E-07 |
| Il6ra-mRNA | CD molecules, Chemokines & Receptors, Cytokines & Receptors, Interleukins | NM_010559.2:2825 | -1.61 | 5.86E-07 |
| Hif1a-mRNA | Apoptosis, Cancer Progression | NM_010431.2:1294 | 0.53 | 1.12E-06 |
| Tnfrsf10b-mRNA | Apoptosis, CD molecules, TNF Superfamily | NM_020275.3:1625 | 0.93 | 1.40E-06 |
| C4b-mRNA | Complement Pathway, Humoral, Inflammation, Innate | NM_009780.2:491 | -2.51 | 6.68E-06 |
| Il1rap-mRNA | Cytokines & Receptors, Inflammation, Innate, Interleukins | NM_008364.2:2415 | 0.84 | 7.95E-06 |
| Cd200-mRNA | CD molecules | NM_010818.3:686 | 1.19 | 8.63E-06 |
| Casp1-mRNA | Cytokines & Receptors, Innate, Interleukins, Microglial Functions | NM_009807.2:259 | 1.13 | 1.76E-05 |
| Gpi1-mRNA | Apoptosis, Cytokines & Receptors, Humoral | NM_008155.4:1540 | 0.53 | 2.43E-05 |
| Mif-mRNA | B-Cell Functions, Cytokines & Receptors, Inflammation, Innate, Transporter Functions | NM_010798.2:373 | 0.62 | 2.84E-05 |
| Vegfa-mRNA | Apoptosis, Cytokines & Receptors, Macrophage Functions, T-Cell Functions | NM_001025250.3:3015 | 1.78 | 2.85E-05 |
| Kit-mRNA | CD molecules, Cytokines & Receptors | NM_001122733.1:4275 | 1.06 | 3.52E-05 |
| Tank-mRNA | Basic Cell Functions, Innate | NM_011529.1:491 | 0.35 | 4.55E-05 |
| Lcp1-mRNA | T-Cell Functions, Transporter Functions | NM_001247984.1:3344 | -0.59 | 5.19E-05 |
| Bax-mRNA | Apoptosis, Transporter Functions | NM_007527.3:735 | 0.49 | 6.44E-05 |
| Atm-mRNA | Apoptosis, B-Cell Functions, Cell Cycle, Senescence | NM_007499.2:5543 | -0.62 | 7.50E-05 |
| App-mRNA | Apoptosis, Cell Cycle, Innate, Transporter Functions | NM_007471.2:511 | 0.64 | 8.04E-05 |