Table E6.
Diagnostic performance of selected characteristics in the determination of peanut allergy, in reduced study cohort used for avidity assays, as governed by the areas under the ROC curve
| Characteristic | AUC | Lower bound (95% CI) | Upper bound (95% CI) |
|---|---|---|---|
| sIgE to peanut (kUA/L) | 0.760 | 0.641 | 0.880 |
| sIgE to Ara h 2 (kUA/L) | 0.944 | 0.885 | 1.000 |
| sIgE to Ara h 6 (kUA/L) | 0.947 | 0.889 | 1.000 |
| Peanut SA (%) | 0.843 | 0.746 | 0.939 |
| Ara h 2 SA (%) | 0.970 | 0.933 | 1.000 |
| Ara h 6 SA (%) | 0.954 | 0.899 | 1.000 |
| PD | 0.931 | 0.866 | 0.995 |
| WD | 0.505 | 0.348 | 0.661 |
| Avidity (%inhibition) | 0.795 | 0.681 | 0.910 |
The AUCs and their respective 95% CIs were generated in the cohort described in Table E1 and allows for comparison of diagnostic performance in the reduced study cohort.